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Published on: October 24, 2015
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Isolated Hepatic Metastasis from Prostate Carcinoma
Stephani C Wang1, Lezah P McCarthy2, Syed Mehdi3
1Department of Medicine, Albany Medical Center, 43 New Scotland Ave., Albany, NY 12208, USA.
Urology Case Reports
|December 14, 2016
Summary
Isolated liver metastasis from prostate cancer is rare but treatable. Surgical removal of isolated liver metastasis in prostate cancer patients can significantly lower prostate-specific antigen (PSA) levels, potentially improving survival.
Area of Science:
- Oncology
- Surgical Oncology
- Urology
Background:
- Prostate cancer is the second most common cancer globally in men.
- Common metastatic sites include lymph nodes and bones.
- Isolated liver metastasis from prostate cancer is an uncommon presentation.
Observation:
- A 75-year-old male with a history of prostate adenocarcinoma presented with rising prostate-specific antigen (PSA).
- Imaging revealed isolated hepatic metastasis.
- The patient underwent a left hepatic lobectomy.
Findings:
- Post-metastasectomy, the patient's PSA levels dramatically decreased to <0.01 ng/mL.
- This indicates a significant response to surgical intervention for isolated liver metastasis.
Implications:
- Physicians should consider isolated liver metastasis in the differential diagnosis for prostate cancer patients with elevated PSA.
- Metastasectomy, combined with medical therapy, may be a viable strategy to prolong overall survival in select cases.
- This case highlights the importance of considering surgical options for rare metastatic patterns in prostate cancer.

