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[Pefloxacin and cat-scratch disease]
1Service de Médecine Interne, maladies infectieuses et tropicales, Centre Hospitalier Intercommunal, Villeneuve-St-Georges.
Pathologie-Biologie
|June 1, 1989
Abstract:
Three patients with cat scratch diseases were treated with pefloxacin (800 mg p.d.). Three of four criteria of the diagnosis were present. The pathogen of the disease is probably an intracellular Gram negative bacilli with a deficient wall. Improvement was obtained in one case and partial response in two other cases.
Insights
Peffloxacin treatment showed improvement in one of three patients with cat scratch disease. Partial responses were observed in two other cases, suggesting potential efficacy against the suspected Gram-negative bacilli pathogen.
Area of Science:
- Infectious Diseases
- Microbiology
- Pharmacology
Background:
- Cat scratch disease (CSD) is a bacterial infection typically caused by Bartonella henselae.
- Diagnosis of CSD can be challenging, often relying on a combination of clinical signs, serology, and PCR.
- The causative agent is suspected to be an intracellular Gram-negative bacillus with a deficient cell wall.