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Acute Bilateral Renal and Splenic Infarctions Occurring during Chemotherapy for Lung Cancer
Noriko Koyama1, Koichi Tomoda, Masayuki Matsuda
1The Second Department of Internal Medicine, Nara Medical University, Japan.
Abstract:
We herein report a rare case of acute bilateral renal and splenic infarctions occurring during chemotherapy for lung cancer. A 60-year-old man presented with acute and intensive upper abdominal and back pain during chemotherapy with cisplatin and etoposide for lung cancer. Contrast-enhanced computed tomography (CT) revealed bilateral renal and splenic infarctions. After the administration of unfractionated heparin his pain was relieved with a clearance of the infarctions in the CT findings and a recovery of renal dysfunction. Enhanced coagulation by lung cancer and arterial ischemia by chemotherapy may therefore contribute to the development of these infarctions.
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