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A Fassio1, L Idolazzi, M Rossini

  • 1Unit of Rheumatology, University of Verona. angelo.fassio@yahoo.it.

Reumatismo
|December 17, 2016
PubMed
Summary
This summary is machine-generated.

Paget

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Area of Science:

  • Orthopedics and Endocrinology
  • Bone Biology and Pathology

Background:

  • Paget's disease of bone (PDB) is a focal skeletal disorder characterized by disorganized bone remodeling.
  • Current treatments primarily involve bisphosphonates.

Observation:

  • A young woman presented with Paget's disease of bone affecting the mandible.
  • The patient experienced a significant diagnostic delay and was initially misdiagnosed and treated with corticosteroids for five years.

Findings:

  • Diagnosis of mandibular Paget's disease was confirmed.
  • Intravenous neridronate treatment led to clinical remission in the patient.

Implications:

  • Highlights the importance of timely diagnosis and appropriate treatment for Paget's disease of bone.
  • Demonstrates the efficacy of neridronate in managing complex cases of Paget's disease of bone, even after diagnostic delays.