A Guide to the PLAZA 3.0 Plant Comparative Genomic Database
Klaas Vandepoele1,2,3
1Department of Plant Systems Biology, VIB, Technologiepark 927, 9052, Ghent, Belgium. klaas.vandepoele@psb.vib-ugent.be.
Methods in Molecular Biology (Clifton, N.J.)
|December 18, 2016
Summary
PLAZA 3.0 is a comparative genomics platform for studying gene families and genome evolution in plants. This online resource aids in translating sequence data into biological insights for over 35 plant species.
Area of Science:
- Genomics
- Bioinformatics
- Plant Biology
Background:
- Comparative genomics facilitates understanding of gene function, genome organization, and evolutionary processes.
- The green plant lineage presents a rich area for genomic research due to its diversity and importance.
Purpose of the Study:
- To introduce PLAZA 3.0, an enhanced online platform for comparative genomics in the green plant lineage.
- To provide a versatile resource for analyzing gene families, genome organization, and evolution.
Main Methods:
- Utilizing genome sequence information from over 35 plant species.
- Precomputing comparative genomic datasets including homologous gene families, multiple sequence alignments, and phylogenetic trees.
- Integrating functional data sets and interactive visualization tools within a user-friendly web interface.
Main Results:
- PLAZA 3.0 offers comprehensive comparative genomic data sets for numerous plant species.
- The platform includes tools for analyzing gene families, sequence alignments, phylogenetic relationships, and genomic colinearity.
- Interactive visualization and a Workbench facilitate data exploration and knowledge discovery.
Conclusions:
- PLAZA 3.0 serves as a valuable starting point for researchers to translate sequence and omics data into biological knowledge.
- The platform enhances the study of genome organization and evolution across the green plant lineage.


