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Research Into Childhood Obstructive Sleep-Disordered Breathing: A Systematic Review
Roderick P Venekamp1, Deepak Chandrasekharan2, Francois Abel3
1Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands.
Chest
|December 19, 2016
Summary
Research on childhood obstructive sleep-disordered breathing (oSDB) has increased, but gaps remain in health services and economics research. Further studies are needed to improve care guidelines for pediatric oSDB.
Area of Science:
- Pediatric Sleep Medicine
- Respiratory Medicine
- Health Services Research
Background:
- Clinical guidelines for childhood obstructive sleep-disordered breathing (oSDB) are debated.
- The optimal care pathway for pediatric oSDB requires further evidence.
- A comprehensive understanding of the research landscape is needed to guide future studies.
Purpose of the Study:
- To systematically review and map existing research on childhood oSDB.
- To identify evidence gaps in the field of pediatric oSDB.
- To support the development of future clinical guidelines and research agendas.
Main Methods:
- Systematic literature search of PubMed, EMBASE, and Cochrane Library up to November 2015.
- Inclusion of all publication types and languages related to childhood oSDB.
- Analysis of publication trends, research themes, and methodologies, with a focus on post-2011 publications.
Main Results:
- Over 5,800 publications on childhood oSDB were included, with 46% published since 2011.
- Most research (61%) focused on treatments, incidence, or prognosis.
- Limited research (2.7%) addressed health services, outcomes, or economics, with observational studies dominating (78.5%).
Conclusions:
- Recent research has expanded the knowledge base for childhood oSDB.
- A significant lack of research in health services, economics, and outcomes hinders the application of current evidence.
- Future research should prioritize these under-explored areas to inform clinical practice and guidelines.
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