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Paget disease: MR imaging findings.
M C Roberts1, H Y Kressel, M D Fallon
1Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia 19104.
Radiology
|November 1, 1989
Summary
Magnetic resonance (MR) imaging effectively identifies Paget disease bone changes and complications. Awareness of MR findings is crucial as its use increases for musculoskeletal imaging.
Area of Science:
- Radiology
- Orthopedics
- Medical Imaging
Background:
- Paget disease of bone is a chronic condition characterized by abnormal bone remodeling.
- Radiographic and computed tomographic (CT) findings are standard for diagnosis.
- Magnetic resonance (MR) imaging is increasingly utilized in musculoskeletal assessments.
Purpose of the Study:
- To correlate MR imaging findings with conventional imaging modalities in Paget disease.
- To describe the spectrum of MR imaging appearances in Paget disease.
- To assess the utility of MR imaging in identifying Paget disease complications.
Main Methods:
- Review of MR images from 13 patients with Paget disease.
- Correlation of MR findings with CT scans, radiographs, and surgical biopsies.
- Analysis of signal intensities on various MR sequences (short and long TR/TE).
Main Results:
- MR imaging findings correlated well with CT and radiographic signs of cortical thickening and bone enlargement.
- Decreased signal intensity on MR indicated dense bone; high-signal foci represented fat collections or fibrovascular marrow.
- MR imaging accurately identified complications such as basilar invagination, spinal stenosis, and sarcoma.
Conclusions:
- MR imaging demonstrates characteristic findings in Paget disease, correlating with other modalities.
- Specific signal characteristics on MR can differentiate bone density and marrow activity.
- Familiarity with MR findings is essential for interpreting studies in patients with Paget disease, especially as MR use expands.