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Castleman's Disease Presenting in the Pelvis.

Ping Wang1, Dan Xia1, Debo Kong1

  • 1Department of Urology, The First Affiliated Hospital, Medical College of Zhejiang University, Hangzhou, Zhejiang Province, China.

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Summary

Castleman's disease (CD) is a rare benign lymphoid disorder. This case report highlights a rare pelvic presentation of localized Castleman's disease, emphasizing its inclusion in pelvic mass differential diagnoses.

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Area of Science:

  • Oncology
  • Pathology
  • Surgical Oncology

Background:

  • Castleman's disease (CD) is a rare benign lymphoid disorder of unknown etiology.
  • It presents in unicentric (localized) and multicentric forms, significantly impacting therapeutic strategies.
  • While the mediastinum is the most common site for localized CD, pelvic occurrences are exceptionally rare.

Purpose of the Study:

  • To report a rare case of pelvic localized Castleman's disease.
  • To emphasize the importance of considering CD in the differential diagnosis of pelvic masses.
  • To illustrate the successful surgical management of this rare condition.

Main Methods:

  • Case report of a 22-year-old female with a pelvic mass.
  • Surgical intervention using robotic-assisted laparoscopic tumorectomy.
  • Pathological examination confirming hyaline-vascular type localized Castleman's disease.

Main Results:

  • A pelvic mass was successfully removed via robotic-assisted laparoscopic surgery.
  • Pathological analysis confirmed the diagnosis of localized Castleman's disease, hyaline-vascular type.
  • The patient's pelvic mass was identified as a rare manifestation of CD.

Conclusions:

  • Castleman's disease, particularly the localized form, should be considered in the differential diagnosis of pelvic masses.
  • Robotic-assisted laparoscopic surgery can be an effective treatment for pelvic localized CD.
  • This case underscores the importance of comprehensive histopathological evaluation for pelvic masses.