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Disorders of sex development (DSD): not only babies with ambiguous genitalia. A practical guide for surgeons

Irene Kearsey1,2, John M Hutson3,4,5

  • 1Department of Paediatrics, University of Melbourne, Melbourne, Australia.

Pediatric Surgery International
|December 20, 2016
PubMed

Insights

This review prepares pediatric surgeons for diagnosing and managing disorders of sex development (DSD) in children. It outlines common clinical scenarios and recommended management pathways for DSD cases.

Area of Science:

  • Pediatric Surgery
  • Endocrinology
  • Genetics

Background:

  • Disorders of sex development (DSD) present complex diagnostic and management challenges in pediatric surgical practice.
  • Early recognition and appropriate management are crucial for optimal patient outcomes.

Purpose of the Study:

  • To equip pediatric surgeons with knowledge of common DSD clinical scenarios.
  • To provide guidance on the diagnosis and management of DSD in pediatric patients.
  • To standardize surgical approaches for DSD cases.

Main Methods:

  • This study is a review of common clinical presentations of DSD in pediatric surgery.
  • It synthesizes information on diagnostic approaches and management strategies.
  • The review focuses on scenarios encountered by surgeons.

Main Results:

  • DSD manifests in neonates with genital abnormalities, children during hernia repair or orchidopexy, and adolescents with pubertal disturbances.
  • The review details clinical features, differential diagnoses, and recommended management pathways for each scenario.
  • Specific surgical contexts like hypospadias correction are also addressed.

Conclusions:

  • Pediatric surgeons must be prepared to identify and manage DSD across various clinical settings.
  • A systematic approach to diagnosis and management is essential for patients with DSD.
  • This review serves as a guide for surgical management of DSD.
Abstract

Keywords:
Childhood adolescenceDSDDiagnosisDisorders of sex development

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