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Updated: Mar 9, 2026

Stereo-Electro-Encephalo-Graphy SEEG With Robotic Assistance in the Presurgical Evaluation of Medical Refractory Epilepsy: A Technical Note
Published on: June 13, 2016
Neuromodulation in refractory epilepsy: Brazilian specialists consensus
Vera Cristina Terra1, Isabella D'Andrea-Meira1, Ricardo Amorim2
1Liga Brasileira de Epilepsia, Comissão de Neuromodulação, São Paulo SP, Brasil.
For drug-resistant epilepsy, vagus nerve stimulation (VNS) and deep brain stimulation (DBS) offer non-pharmacological treatment options. This paper provides recommendations for VNS and DBS use in Brazilian patients with refractory epilepsy.
Area of Science:
- Neurology
- Neurosurgery
Background:
- Epilepsy is a serious neurological disorder defined by recurrent seizures.
- Medically refractory epilepsy poses significant challenges, necessitating alternative treatments.
- Non-pharmacological therapies are crucial for managing difficult-to-treat epilepsy cases.
Framework:
- Palliative surgical interventions like Vagus Nerve Stimulation (VNS) and Deep Brain Stimulation (DBS) are considered for refractory epilepsy.
- These neuromodulation techniques aim to reduce seizure frequency and severity.
- Evidence-based guidelines are essential for optimal patient selection and management.
Implementation:
- This paper focuses on providing recommendations for VNS and DBS implementation.
- The guidelines are specifically tailored for the Brazilian healthcare context.
- Consideration is given to the practical aspects of applying these advanced therapies.
Implications:
- The recommendations aim to improve the management of refractory epilepsy in Brazil.
- Wider adoption of VNS and DBS could enhance patient quality of life.
- This work contributes to the advancement of epilepsy treatment strategies in the region.
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Published on: December 18, 2016
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Seizures are typically classified into two main categories: focal and generalized seizures.
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Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types: