N,B-Bidentate Boryl Ligand-Supported Iridium Catalyst for Efficient Functional-Group-Directed C-H Borylation

Area of Science:

• Organometallic Chemistry
• Catalysis
• Synthetic Chemistry

Background:

• Transition metal complexes are crucial catalysts in organic synthesis.
• Developing efficient methods for ligand synthesis and metal complex formation is essential.
• Silylboranes offer unique reactivity for introducing boron-containing ligands.

Purpose of the Study:

• To design and synthesize novel silylborane precursors.
• To utilize these precursors for the formation of iridium(III) complexes.
• To develop a catalytic ortho-borylation reaction of arenes.

Main Methods:

• Synthesis of silylborane precursors.
• Formation of iridium(III) complexes via Si-B oxidative addition.
• In situ catalyst generation using silylborane preligand 3c and [IrCl(COD)]2 for borylation.

Main Results:

• Convenient silylborane precursors were successfully designed and prepared.
• Iridium(III) complexes were readily formed through Si-B oxidative addition.
• An efficient catalytic ortho-borylation of various arenes was achieved.

Conclusions:

• The developed silylborane precursors are effective for N,B-bidentate boryl ligand introduction.
• The catalytic system provides a practical and efficient route for arene ortho-borylation.
• This work expands the utility of silylboranes in organometallic chemistry and catalysis.