Gene expression profiles and physiological data from mice fed resveratrol-enriched rice DJ526

Area of Science:

• Biochemistry
• Genetics
• Gerontology

Background:

• The molecular mechanisms of resveratrol's lifespan-extending effects are not fully understood.
• Resveratrol-enriched rice (DJ526) was developed to facilitate research into these mechanisms.
• DJ526 contains significant levels of resveratrol and has shown anti-aging effects in mice.

Purpose of the Study:

• To provide raw data sets for the analysis of resveratrol's anti-aging effects.
• To support further investigation into the molecular pathways involved in aging and resveratrol's action.
• To present a method for micron-level blood serum analysis.

Main Methods:

• Microarray analysis of gene expression in mice fed DJ526 and control rice.
• Collection of physiological data from mice, including motor coordination, physical strength, and skin aging.
• Development of a method for micron-level blood serum analysis.

Main Results:

• Raw data from microarray and physiological assessments are publicly available.
• Data demonstrate the effects of DJ526 and resveratrol on age-related parameters in mice.
• A novel method for detailed blood serum analysis was established.

Conclusions:

• The provided data sets can accelerate research into the anti-aging properties of resveratrol.
• These resources may uncover new insights into the etiology of aging and resveratrol-induced signaling pathways.
• Further research using these data can elucidate the role of DJ526 rice in promoting longevity.