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[Collagen plastic surgery in progressive myopia].

A V Svirin, O A Antipova, Z P Milovanova

    Vestnik Oftalmologii
    |July 1, 1989
    PubMed
    Summary

    This study demonstrates collagen sponge implants effectively halt myopia progression in 95% of patients. The surgical technique improves vision and reduces refractive error, offering a safe option for progressive myopia.

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    Experimental Study of the Possibility of Culturing of Mesenchymal Stromal Cell and Induction of Osteogenic Differentiation on Collagen-Based Scaffolds of Various Modifications.

    Bulletin of experimental biology and medicine·2020

    Area of Science:

    • Ophthalmology
    • Regenerative Medicine
    • Biomaterials

    Background:

    • Progressive myopia poses a significant challenge in ophthalmology.
    • Current treatments for high myopia often have limitations or complications.
    • The development of innovative surgical techniques is crucial for managing myopia progression.

    Purpose of the Study:

    • To evaluate the efficacy and safety of collagen sponge implants for treating progressive myopia.
    • To assess the impact of the surgical intervention on visual acuity, refractive error, and ocular hemodynamics.

    Main Methods:

    • Surgical implantation of collagen sponges into Tenon's space in 200 eyes (100 patients) with myopia ranging from 3.5 to 15 diopters.
    • Experimental studies on rabbits to analyze episcleral tissue response to collagen implants.

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  • Post-operative monitoring of visual acuity, clinical refraction, and ocular hemodynamics.

    • Main Results:

    • Myopia progression halted in 95% of operated eyes.
    • Significant improvement in visual acuity (0.14-0.15) and reduction in clinical refraction (0.9-1.0 diopters) in 84% of patients.
    • Enhanced episcleral connective tissue formation, improved ocular hemodynamics, and increased eye membrane rigidity (1.5-2 fold).

    Conclusions:

    • Collagen plastic surgery using sponge implants is a highly effective and safe method for treating progressive myopia.
    • The procedure demonstrates a high success rate in halting myopia progression and improving visual outcomes.
    • The simplicity, material availability, and low complication rate make this technique suitable for myopia exceeding 4.0-5.0 diopters.