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Related Experiment Videos

[Long-term therapy with the insulin pump].

B Podrouzková

    Vnitrni Lekarstvi
    |August 1, 1989
    PubMed
    Summary

    Insulin pump therapy effectively managed diabetes in 179 patients, improving metabolic control and reducing complications. While technical issues and patient adherence posed challenges, long-term insulin pump use shows significant benefits for specific diabetes types.

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    [Combined therapy with insulin/gliquidone (Glurenorm) in type 2 diabetes after treatment failure using oral antidiabetic agents].

    Vnitrni lekarstvi·1992

    Area of Science:

    • Endocrinology
    • Metabolic Diseases
    • Medical Device Technology

    Context:

    • Diabetes mellitus management presents ongoing challenges, particularly in maintaining metabolic compensation and preventing long-term complications.
    • Insulin pump therapy offers a continuous subcutaneous insulin infusion method, an alternative to multiple daily injections.
    • Patient adherence to diet and device management are critical factors in the success of insulin pump therapy.

    Purpose:

    • To evaluate the long-term effectiveness and safety of insulin pump therapy in a cohort of 179 patients with type I and type II diabetes mellitus.
    • To assess the impact of insulin pump treatment on metabolic compensation indicators, blood lipid levels, and specific diabetes-related complications.
    • To identify factors influencing treatment success and failure, including technical issues and patient adherence.

    Summary:

    • Long-term insulin pump treatment in 179 diabetic patients (type I and II) demonstrated high success rates (96.7%), with significant improvements in metabolic compensation, triacylglycerol, and cholesterol levels.
    • Complications were primarily technical (43 pump failures) or due to poor patient adherence (6 treatment failures).
    • Favorable impacts were observed on proteinuria and neuropathy, while long-term suppression of specific complication progression remains under investigation.

    Impact:

    • Insulin pump therapy is a valuable tool for managing metabolic lability in type I diabetes and aiding weight reduction in obese type II diabetics with insulin resistance.
    • The findings support the use of insulin pumps for improved glycemic control and potential reduction in diabetes-related complications.
    • Further research is needed to definitively establish the long-term efficacy of insulin pumps in halting the progression of specific diabetes complications.

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