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Published on: November 4, 2015
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Inflammatory Pseudotumor Originating from the Right Ventricular Outflow Tract
Mohita Singh1, Umair Khalid1, Nasser Lakkis1
1Sect. of Cardiology, Department of Medicine, Baylor College of Medicine, 1 Baylor Plaza, Houston, TX 77030, USA.
Case Reports in Cardiology
|December 23, 2016
Summary
This case report details a rare IgG4-related inflammatory pseudotumor in the heart of a young man. Treatment with oral prednisone effectively reduced the cardiac mass size.
Area of Science:
- Cardiology
- Pathology
- Immunology
Background:
- Inflammatory pseudotumor is a rare condition.
- Cardiac origin of inflammatory pseudotumor is exceedingly rare.
- IgG4-related disease is a systemic fibroinflammatory condition.
Purpose of the Study:
- To report an exceedingly rare case of cardiac inflammatory pseudotumor.
- To highlight the diagnostic and therapeutic approach for this entity.
- To emphasize the importance of considering rare tumors in the differential diagnosis of intracardiac masses.
Main Methods:
- Transthoracic echocardiogram to visualize the cardiac mass.
- Computed tomography-guided biopsy for tissue diagnosis.
- Histopathological examination to confirm IgG4-related inflammatory pseudotumor.
- Treatment with oral prednisone.
Main Results:
- A 4 × 2.5 cm mass was identified originating from the right ventricle outflow tract extending into the aortic root.
- Biopsy confirmed IgG4-related inflammatory pseudotumor.
- Oral prednisone treatment resulted in a reduction in mass size.
Conclusions:
- Cardiac inflammatory pseudotumors are rare and should be considered in the differential diagnosis of intracardiac tumors.
- IgG4-related inflammatory pseudotumors can occur in the heart.
- Early diagnosis and appropriate treatment can lead to favorable outcomes.
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