Related Experiment Video
Updated: Mar 9, 2026

Protocol for Relative Hydrodynamic Assessment of Tri-leaflet Polymer Valves
Published on: October 17, 2013
A global perspective on mechanical prosthetic heart valve thrombosis: Diagnostic and therapeutic challenges
Mustafa Ozan Gürsoy1, Macit Kalçık2, Mahmut Yesin3
1Department of Cardiology, Gaziemir State Hospital; İzmir-Turkey. m.ozangursoy@yahoo.com.
Abstract:
Prosthetic valve thrombosis is one of the major causes of primary valve failure, which can be life-threatening. Multimodality imaging is necessary for determination of leaflet immobilization, cause of underlying pathology (thrombus versus pannus or both), and whether thrombolytic therapy attempt in the patient would be successful or surgery is needed. Current guidelines for the management of prosthetic valve thrombosis lack definitive class I recommendations due to lack of randomized controlled trials, and usually leave the choice of treatment to the clinician's experience. In this review, we aimed to summarize the pathogenesis, diagnosis, and management of mechanical prosthetic valve thrombosis.
Related Concept Videos
Venous Thrombosis III: Interprofessional Care
Mitral Stenosis III: Medical Management
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
Mitral Valve Prolapse II: Assessment and Management
Cardiac Catheterization III: Left Heart Catheterization
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies

