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Case 237: Renal Cell Carcinoma with Osseous Metaplasia
Billy Ming Hei Lai1, Solomon Yig Joon Ka1, Wai Kuen Kan1
1From the Departments of Radiology (B.M.H.L., S.Y.J.K., W.K.K., T.F.L., J.L.S.K.) and Clinical Pathology (M.W.L., Y.H.L.), Pamela Youde Nethersole Eastern Hospital, 3 Lok Man Road, Chai Wan, Hong Kong.
Abstract:
History A 47-year-old man presented with palpitations and decreased exercise tolerance. A peripheral blood smear revealed anemia, thrombocytopenia, and blast cells, and a diagnosis of acute myeloid leukemia was made. Immunohistochemistry revealed positivity for cluster of differentiation (or CD) markers, which have been reported to be associated with an increased risk of extramedullary leukemic involvement. Thus, contrast material-enhanced computed tomography (CT) of the thorax, abdomen, and pelvis was requested to enable exclusion of any extramedullary extension of leukemia. Unenhanced and contrast-enhanced nephrographic phase CT was performed. Follow-up CT 3 months later showed minimal interval change in the lesion (images not shown).
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