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Updated: Mar 9, 2026

Intraoperative Assessment of Resection Margins in Oral Cavity Cancer: This is the Way
Published on: May 10, 2021
Recurrent oral cavity cancer: Patterns of failure after salvage multimodality therapy
Sean R Quinlan-Davidson1, William H Morrison1, Jeffrey N Myers2
1Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas.
Background:
We focused on a cohort of radiation naïve patients who had recurrent oral cavity cancer (recurrent OCC) to assess their outcomes with salvage multimodal therapy.
Methods:
A retrospective single institutional study was performed of patients with recurrent OCC. Disease recurrence and survival outcomes were assessed.
Results:
Seventy-eight patients were analyzed. All patients had salvage surgery and intensity-modulated radiotherapy (IMRT) and 74% had chemotherapy. Five-year overall survival, recurrence-free survival, and locoregional control rates were 59%, 60%, and 74%, respectively.
Conclusion:
Outcomes of radiation naïve patients with recurrent OCC are fair, and seem similar with patients with locally advanced nonrecurrent OCC treated with multimodal therapy. © 2016 Wiley Periodicals, Inc. Head Neck 39: 633-638, 2017.
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