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Atomic Force Microscopy

Atomic Force Microscopy

Atomic force microscopy (AFM) is a type of scanning probe microscopy that can analyze topographic details of various specimens like ceramics, glass, polymers, and biological samples. AFM offers over 1000 times more resolution than the optical imaging system. Images generated from AFM are three-dimensional surface profiles, offering an advantage over the flat, two-dimensional images from other imaging techniques.
The AFM Probe
The probe is regarded as the heart of any AFM setup and comprises the...

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Updated: May 6, 2026

Assessment of Boron Doped Diamond Electrode Quality and Application to In Situ Modification of Local pH by Water Electrolysis

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Published on: January 6, 2016

Hyperpolarized Nanodiamond Surfaces.

Ewa Rej¹, Torsten Gaebel¹, David E J Waddington¹

¹ARC Centre of Excellence for Engineered Quantum Systems, School of Physics, University of Sydney , Sydney, New South Wales 2006, Australia.

Journal of the American Chemical Society

|December 24, 2016

Summary

This summary is machine-generated.

Nanodiamonds can hyperpolarize liquid compounds using surface electron spins for magnetic resonance imaging. This technique distinguishes surface from bulk liquid spins, aiding controlled drug release signaling.

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Area of Science:

Biomedical engineering
Quantum mechanics
Magnetic resonance imaging

Background:

Nanodiamonds are widely used biomedical platforms due to their non-toxicity and unique quantum properties.
Current applications include drug delivery, imaging, and subcellular tracking.
The potential for nanodiamonds in magnetic resonance has not been fully explored.

Purpose of the Study:

To investigate the use of nanodiamond surface electron spins for hyperpolarizing adsorbed liquid compounds.
To explore the application of this phenomenon in magnetic resonance at low fields and room temperature.
To differentiate surface and bulk liquid spins using combined relaxation and hyperpolarization measurements.

Main Methods:

Utilizing intrinsic electron spins on nanodiamond surfaces.
Employing hyperpolarization techniques at low magnetic fields and room temperature.
Combining relaxation measurements with hyperpolarization data.

Main Results:

Demonstrated successful hyperpolarization of adsorbed liquid compounds by nanodiamond surface spins.
Achieved differentiation between surface and bulk liquid spins.
Established a method to distinguish spins based on their location relative to the nanodiamond surface.

Conclusions:

Nanodiamonds can serve as a platform for magnetic resonance hyperpolarization.
This technique offers potential for signaling controlled release of pharmaceutical payloads.
The findings expand the utility of nanodiamonds in biomedical applications.