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Related Experiment Videos

[Our experience in using the triphasic contraceptive trisiston for contraception].

D Vasilev, M Katsarova, I Dikov

    Akusherstvo I Ginekologiia
    |January 1, 1989
    PubMed
    Summary

    Trisistone, a triphasic oral contraceptive, demonstrated high contraceptive efficiency in 80 women over 250 cycles. Mild side effects were noted, with irregular bleeding being the primary concern for discontinuation.

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    [Prevention of neural tube defects with folic acid].

    Akusherstvo i ginekologiia·2003

    Area of Science:

    • Reproductive Medicine
    • Pharmacology

    Context:

    • Triphasic oral contraceptives offer potential advantages in hormonal balance.
    • Trisistone, a specific triphasic preparation, was evaluated for its efficacy and tolerability.
    • Limited application of such preparations in the country necessitated this study.

    Purpose:

    • To assess the contraceptive efficiency of Trisistone.
    • To evaluate the side effect profile and patient tolerance of Trisistone.
    • To determine the suitability of Trisistone as an initial oral contraceptive.

    Summary:

    • A study involving 80 women and 250 cycles found Trisistone to be highly effective, with no pregnancies recorded.
    • Reported side effects were generally mild, occurring in 2.4% to 9.7% of cycles.
    • Irregular bleeding was the main reason for patient-reported discontinuation.
    Keywords:
    BleedingContraceptionContraceptive EffectivenessContraceptive MethodsDiseasesEvaluationFamily PlanningOral ContraceptivesOral Contraceptives, CombinedOral Contraceptives, PhasicSigns And SymptomsUse-effectiveness

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    Impact:

    • Trisistone shows promise as an initial oral contraceptive option, similar to "mini-dose" preparations.
    • Recommendations include continued use for well-tolerated cases and switching contraceptives if irregular bleeding occurs.
    • This research provides valuable data on a novel contraceptive approach for clinical consideration.