[Effect of acute preoperative hemodilution on circulation, oxygen budget and blood coagulation]

The effect of acute preoperative hemodilution on circulation, oxygen budget and blood coagulation has been studied in 54 patients with lung pathology and major vessel disease. With exfusion up to 20% circulating blood volume (CBV), circulatory changes were manifested in decreased vascular tone. With exfusion up to 25% CBV, an increase in cardiac output and a decrease in mean blood pressure were observed. O2 transport, consumption and utilization remained unchanged, with normalization of a so far enhanced blood coagulation.