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Related Experiment Videos

Complement activity and selected hematologic variables in newborn foals fed bovine colostrum.

J P Lavoie1, M S Spensley, B P Smith

  • 1Department of Medicine, School of Veterinary Medicine, University of California, Davis 95616.

American Journal of Veterinary Research
|September 1, 1989
PubMed
Summary

Newborn foals fed bovine colostrum showed normal complement activity and hematologic development, similar to those nursing their dams. Bovine colostrum did not cause hemolysis in foal red blood cells (RBCs).

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Area of Science:

  • Veterinary Immunology
  • Neonatal Equine Health
  • Comparative Mammalian Nutrition

Background:

  • Neonatal isoerythrolysis (NI) is a concern in foals.
  • Colostrum provides crucial passive immunity to foals.
  • Bovine colostrum is sometimes used as a substitute for mare's milk.

Purpose of the Study:

  • To evaluate serum complement activity and hematologic variables in foals fed bovine colostrum.
  • To assess the presence of anti-equine antibodies in bovine colostrum.
  • To compare the effects of bovine colostrum versus nursing on foal health.

Main Methods:

  • Serum complement activity (hemolytic and conglutinating) was measured.
  • Hematologic variables, including red blood cell (RBC) osmotic fragility, were assessed.

Related Experiment Videos

  • Bovine colostrum was tested for anti-equine antibodies and its effect on foal RBCs.

    • Main Results:

    • Foals fed bovine colostrum exhibited normal increases in complement activity, reaching adult levels.
    • Physiologic anemia occurred in both groups, with no significant change in RBC osmotic fragility after bovine colostrum.
    • Bovine colostrum agglutinated foal RBCs but did not cause hemolysis.

    Conclusions:

    • Bovine colostrum can be safely administered to newborn foals without causing hemolysis.
    • Foals fed bovine colostrum demonstrate normal immune and hematologic development.
    • Bovine colostrum may serve as a viable alternative for passive transfer in foals when mare's colostrum is unavailable.