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The Use of Different Irrigation Techniques to Decrease Bacterial Loads in Healthy and Diabetic Patients with
Mai Ghoneim1, Shehab ElDin Saber2, Tarek El-Badry3
1Endodontics Department, National Research Centre, Cairo, Egypt.
The EndoVac system effectively reduced root canal bacteria, particularly in diabetic patients. This endodontic irrigation technique shows promise for managing apical periodontitis, especially in compromised individuals.
Area of Science:
- Endodontics
- Microbiology
- Diabetology
Background:
- Diabetes mellitus impairs host immunity, exacerbating apical periodontitis.
- Increased bacterial virulence in diabetic patients complicates endodontic treatment outcomes.
Purpose of the Study:
- To compare bacterial reduction using conventional irrigation versus the EndoVac system.
- To evaluate efficacy in systemically healthy and diabetic patients with apical periodontitis.
Main Methods:
- Selected key periodontitis bacteria: Enterococcus faecalis, Peptostreptococcus micros, Fusobacterium necleatum.
- Bacterial samples from root canals before and after cleaning/shaping.
- Quantitative polymerase chain reaction (qPCR) for bacterial count analysis.
Main Results:
- EndoVac system demonstrated significant bacterial reduction compared to conventional irrigation.
- Enhanced efficacy of EndoVac observed for Peptostreptococcus micros in diabetic patients.
Conclusions:
- EndoVac irrigation is a promising adjunct for bacterial clearance in root canals.
- Further research is needed to optimize bacterial removal in immunocompromised individuals.
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