Related Experiment Video
Updated: Mar 9, 2026

A Murine Model of Group B Streptococcus Vaginal Colonization
Published on: November 16, 2016
Case Series Description and Genomic Characterization of Invasive Group A Streptococcal Infections in Pediatric
Jennifer Dien Bard1, Kanokporn Mongkolrattanothai, Priyanka Kachroo
1From the *Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, California; †Keck School of Medicine at the University of Southern California, Los Angeles, California; ‡Division of Infectious Diseases, Department of Pediatrics, Children's Hospital Los Angeles, Los Angeles, California; §Center for Molecular and Translational Human Infectious Diseases Research; and ¶Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas.
Abstract:
We report an unusual cluster of invasive group A Streptococcus infections in 6 pediatric patients and demonstrate that the strains were derived from diverse genetic backgrounds, confirming the occurrence of a community cluster rather than a clonal outbreak. Whole genome sequencing provided a rapid and comprehensive view of group A Streptococcus genotypes and helped guide our institutional response and public health maneuvers.
Related Concept Videos
Acute Pyelonephritis II: Diagnostic Studies and Management
Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
Factors Affecting the Risk of Infection
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...

