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INPP5E Preserves Genomic Stability through Regulation of Mitosis

Elizabeth A Sierra Potchanant1, Donna Cerabona1,2, Zahi Abdul Sater1

  • 1Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana, USA.

Molecular and Cellular Biology
|December 30, 2016
PubMed
Summary

The inositol polyphosphate-5-phosphatase INPP5E is crucial for cell division, ensuring proper chromosome segregation and preventing aneuploidy. This discovery highlights INPP5E's vital role in cellular homeostasis and development.

Keywords:
INPP5Eaneuploidycell cyclecentrosomesmitosisspindle assembly checkpoint

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