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Indirect Effects of Pneumococcal Conjugate Vaccines in National Immunization Programs for Children on Adult
Young Keun Kim1, David LaFon2, Moon H Nahm3
1Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea.
Abstract:
The pneumococcal conjugate vaccine (PCV) was developed to overcome the limitations of the pneumococcal polysaccharide vaccine, which produces poor immunogenicity in infants younger than 2 years. As many countries have included PCVs in national immunization programs for children, the incidence of invasive pneumococcal disease caused by vaccine type Streptococcus pneumoniae has declined markedly, not only among the vaccinated pediatric population, but also among unvaccinated adults. In this review, we present a concise overview of the indirect effects of mass pediatric PCV immunization on unvaccinated adults.
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