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Spine radiosurgery: lessons learned from the first 100 treatment sessions
Ran Harel1,2,3, Raphael Pfeffer4, Daphne Levin4
11Stereotactic Radiosurgery Unit and.
Neurosurgical Focus
|January 3, 2017
Summary
Spinal radiosurgery (SRS) offers a safe and effective noninvasive treatment for spine tumors, achieving a 95% local control rate. Comprehensive team education is key to minimizing the learning curve
Area of Science:
- Oncology
- Radiotherapy
- Neurosurgery
Background:
- Local therapy is effective for selected spine tumors.
- Spinal radiosurgery (SRS) is an evolving noninvasive radiotherapy technique.
- The learning curve for new technologies can impact outcomes.
Purpose of the Study:
- To analyze the outcomes of the first 100 spinal radiosurgery (SRS) procedures.
- To evaluate the impact of the learning curve on SRS treatment efficacy.
- To assess the safety and effectiveness of SRS for spine tumors.
Main Methods:
- Retrospective analysis of SRS data from Sheba Medical Center and Assuta Medical Centers (Sep 2011 - Feb 2016).
- Collection and analysis of patient history, clinical/neurological findings, pathology, SRS variables, complications, and follow-up data.
- Calculation of local control rates and qualitative study of treatment failures.
Main Results:
- 100 SRS sessions treated 118 lesions across 179 spinal levels in 80 patients.
- Low complication rates observed, not correlated with the learning curve.
- Overall local control rate was 95%, dose-dependent (87% at 16 Gy, 97% at 18 Gy).
Conclusions:
- Spinal radiosurgery (SRS) is a safe and effective local treatment for spine tumors.
- Dose escalation to 18 Gy improved local control rates.
- Comprehensive team education and communication are crucial for successful SRS implementation.

