Related Experiment Video
Updated: Mar 9, 2026
A Three-Dimensional Spheroid Model to Investigate the Tumor-Stromal Interaction in Hepatocellular Carcinoma
Published on: September 30, 2021
Epidemiology and treatment of hepatocellular carcinoma in Thailand
Soonthorn Chonprasertsuk1, Ratha-Korn Vilaichone1
1Gastroenterology unit, Department of Medicine, Thammasat University Hospital, Pathumthani, Thailand.
Insights
Hepatocellular carcinoma (HCC) is a common liver cancer in Thailand, often linked to chronic hepatitis B virus (HBV) infection. Early detection and prevention of HBV transmission are key to improving outcomes for this prevalent malignancy.
Area of Science:
- Hepatology
- Oncology
- Infectious Diseases
Background:
- Hepatocellular carcinoma (HCC) is the most frequent malignant liver tumor in Thailand.
- High incidence rates are linked to endemic chronic hepatitis B virus (HBV) infection.
- Many patients present with advanced HCC, facing limited treatment options and poor prognosis.
Purpose of the Study:
- To provide an updated overview of Hepatocellular Carcinoma (HCC) in Thailand.
- To cover epidemiology, diagnosis, clinical manifestations, and treatment strategies for HCC.
Main Methods:
- Review and synthesis of current information on HCC in Thailand.
- Analysis of diagnostic criteria and staging systems, including the Barcelona Clinic Liver Cancer (BCLC) system.
- Examination of treatment modalities based on HCC stage.
Main Results:
- HCC is a significant public health issue in Thailand, predominantly associated with HBV.
- The BCLC staging system guides treatment, differentiating between curative and palliative approaches.
- Preventive measures, including HBV vaccination and infection treatment, are crucial.
Conclusions:
- Effective HCC management in Thailand requires a comprehensive approach, from prevention to tailored treatment.
- Addressing chronic HBV infection is paramount for reducing HCC incidence and improving patient survival.
- Continued updates on HCC epidemiology and treatment are essential for clinical practice.
Abstract:
Hepatocellular carcinoma (HCC) is the most frequent type of malignant liver tumor in Thailand. The high incidence rate of HCC reflects from chronic HBV infection in this endemic area. Some patients are asymptomatic at presentation whereas many of them presented at advanced stage of HCC with limited treatment options and grave outcome. The Barcelona Clinic Liver Cancer (BCLC) staging system and management allocation for HCC is widely accepted and used in many international guidelines including Thailand. Curative treatment is expected in early stage of HCC while palliative treatment, combination treatment and best supportive care are offered to advanced stage of HCC. The most effective strategy to prevent the development of HCC is prevention of HBV vertical transmission and treatment HBV or HCV infection. The purpose of this article is to update information of HCC in Thailand including epidemiology, diagnosis, clinical manifestation, and treatment.
More Related Videos
06:38An Oncogenic Hepatocyte-Induced Orthotopic Mouse Model of Hepatocellular Cancer Arising in the Setting of Hepatic Inflammation and Fibrosis
Published on: September 12, 2019
09:11Y-90 Radioembolization and PD-1 Inhibitor as Neoadjuvant Treatment in Hepatocellular Carcinoma
Published on: May 24, 2024
