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Glucose homeostasis abnormalities among Cameroon patients with newly diagnosed hypertension

Félicité Kamdem1,2, Daniel Lemogoum2, Marie-Solange Doualla1,3

  • 1Internal Medicine Unit, Douala General Hospital, Douala, Cameroon.

Journal of Clinical Hypertension (Greenwich, Conn.)
|January 3, 2017
PubMed

Insights

Glucose homeostasis abnormalities are common in Cameroonians with new hypertension. Factors like male sex, older age, and high LDL cholesterol increase risk.

Area of Science:

  • Endocrinology
  • Cardiovascular Medicine
  • Public Health

Background:

  • Hypertension and glucose metabolism disorders are significant global health issues.
  • Understanding the co-occurrence of these conditions in specific populations is crucial for effective management.
  • Cameroon faces a growing burden of non-communicable diseases, including hypertension and diabetes.

Purpose of the Study:

  • To determine the prevalence of glucose homeostasis abnormalities in newly diagnosed hypertensive patients in Cameroon.
  • To identify factors associated with abnormal glucose metabolism in this patient group.

Main Methods:

  • A cross-sectional survey was conducted with 839 newly diagnosed hypertensive patients at Douala General Hospital.
  • Data collected included blood pressure, fasting plasma glucose (FPG), and lipid profiles.
  • Statistical analysis, including multivariable logistic regression, was used to identify associated factors.

Main Results:

  • 38.3% of participants exhibited abnormal glucose homeostasis.
  • Prevalence of impaired fasting glycemia was 23.7%, and provisional diabetes was 6.8%.
  • Male sex, age over 55, and elevated LDL cholesterol (>1 g/L) were independently associated with abnormal glucose homeostasis.

Conclusions:

  • Glucose homeostasis abnormalities are highly prevalent in Cameroonian patients with newly diagnosed hypertension.
  • These findings highlight the need for screening for glucose metabolism disorders in hypertensive individuals in this region.
  • Early identification and management of these co-existing conditions can improve patient outcomes.

Keywords:
Camerooncardiovascular risk factorsdiabetesglucose homeostasis abnormalitieshypertensionimpaired fasting glycemiaprovisional diabetes

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