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Pulmonary infections after tuberculosis

Kauser Jabeen1

  • 1Department of Pathology and Laboratory Medicine, Aga Khan University, Stadium Road, Karachi, Pakistan.

International Journal of Mycobacteriology
|January 4, 2017
PubMed
Abstract

Insights

Pulmonary tuberculosis survivors face risks of secondary infections like chronic pulmonary aspergillosis and nontuberculous mycobacterial infections. Effective management is crucial due to diagnostic and treatment challenges in high-burden countries.

Area of Science:

  • Pulmonary medicine
  • Infectious diseases
  • Public health

Background:

  • Pulmonary tuberculosis (TB) treatment can cause lung damage, leading to complications like repeated infections.
  • These secondary infections are often misdiagnosed as TB recurrence, hindering effective treatment.
  • The severity of post-TB infections correlates with lung damage, particularly in bronchiectasis and fibrocavitary diseases.

Purpose of the Study:

  • To review the epidemiology, treatment, and management of infections following tuberculosis.
  • To highlight the public health impact of these post-TB infections in high-burden nations.

Main Methods:

  • Literature review of published articles and review papers.

Main Results:

  • Patients with post-TB lung damage are susceptible to chronic pulmonary aspergillosis and nontuberculous mycobacterial infections.
  • High prevalence of chronic pulmonary aspergillosis exists in TB-endemic regions.
  • Previous TB infection elevates the risk of acquiring nontuberculous mycobacterial infections.

Conclusions:

  • Limited diagnostic tools and antimicrobial availability in high-TB-burden countries create significant management challenges.
  • These post-TB infections negatively impact patient outcomes and strain public health resources.
Keywords:
Chronic pulmonary aspergillosisDeveloping countriesNon tuberculous mycobacterial infectionsPost TB infections

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