Related Experiment Video
Updated: Mar 9, 2026
09:33
Phthalic Acid Ester-Binding DNA Aptamer Selection, Characterization, and Application to an Electrochemical Aptasensor
Published on: March 21, 2018
10.4K
Precipitation SELEX: identification of DNA aptamers for calcium phosphate materials synthesis
K R Baillargeon1, K Meserve1, S Faulkner1
1Department of Chemistry and Physics, Emmanuel College, 400 The Fenway, Boston, MA, USA. gerdoar@emmanuel.edu.
Chemical Communications (Cambridge, England)
|January 4, 2017
Abstract:
DNA aptamers that enhance calcium phosphate mineral formation were identified using a novel precipitation SELEX method. The evolved DNA library was substantially enriched in G nucleotides and in predicted G-quadruplex structures, suggesting their importance in the mechanism of mineralization. This work could readily be extended to provide additional novel DNA aptamers for materials synthesis.
