Related Experiment Video
Updated: Mar 9, 2026
08:12
Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
Published on: May 26, 2023
2.6K
Redo Mitral Valve Replacement for Prosthetic Valve Thrombosis: Single Center Experience
Jignesh Kothari1, Kartik Patel2, Bhavin Brahmbhatt3
1Professor, Department of Cardiothoracic and Vascular Surgery, U. N. Mehta, Institute of Cardiology and Research Center , New Civil Hospital Campus, Asarwa, Ahmedabad, Gujarat, India .
Journal of Clinical and Diagnostic Research : JCDR
|January 5, 2017
Summary
Prosthetic Valve Thrombosis (PVT) is a serious complication after valve replacement. Redo mitral valve surgery for PVT carries a high mortality risk, especially in unstable patients.
Area of Science:
- Cardiovascular Surgery
- Cardiac Valve Disease
- Thrombosis Research
Background:
- Prosthetic Valve Thrombosis (PVT) significantly increases morbidity and mortality post-valve replacement.
- While surgery is often life-saving for obstructive PVT, optimal treatment strategies require further investigation.
Purpose of the Study:
- To identify risk factors and outcomes for patients undergoing redo mitral valve surgery due to acute PVT.
- To analyze pre-operative, intra-operative, and post-operative factors influencing patient outcomes.
Main Methods:
- A retrospective study of 65 patients who underwent redo mitral valve surgery for obstructive PVT between January 2012 and February 2015.
- Exclusion criteria included acute PVT of the aortic valve or combined valves.
- Data collected included pre-operative, intra-operative, and post-operative factors, along with follow-up data.
Main Results:
- The overall mortality rate was 29.2% (19/65).
- Mortality was significantly higher in patients undergoing direct surgery (46%) compared to those with failed thrombolysis (10%).
- Higher mortality was observed in patients with New York Heart Association (NYHA) III/IV class compared to NYHA I/II class (p=0.02).
Conclusions:
- PVT remains a challenging post-operative complication with high mortality, irrespective of treatment.
- Surgical management of PVT, though life-saving, poses significant risks, particularly for hemodynamically unstable patients or those in NYHA class III/IV.
Related Concept Videos
01:26Mitral Stenosis III: Medical Management
398
Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
398
01:25Mitral Regurgitation III: Medical Management
475
Mitral regurgitation (MR) is characterized by retrograde blood circulation from the left ventricle into the left atrium due to inadequate mitral valve closure. The severity of the condition, symptoms, and underlying cause determine treatment strategies.Monitoring and Pharmacological TreatmentPatients with mild to moderate MR typically do not need immediate intervention but regular monitoring to assess progression and guide treatment. Patients with mild MR should have an echocardiogram every 3-5...
475
01:20Mitral Regurgitation I: Introduction
802
Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
802
01:22Mitral Stenosis I: Introduction
1.0K
Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
1.0K
01:27Mitral Valve Prolapse I: Introduction
813
IntroductionThe mitral valve, one of the heart's four valves, regulates blood flow. These valves have flaps that open and close to direct blood properly through the heart and body. During each heartbeat, the flaps open for blood to pass through and seal shut to prevent backflow. Specifically, the mitral valve opens to allow blood flow from the heart's upper left chamber to the lower left chamber. It then closes securely as the lower left chamber contracts to pump blood to the body, preventing...
813
01:22Mitral Valve Prolapse II: Assessment and Management
898
IntroductionA range of clinical features characterizes Mitral Valve Prolapse (MVP), but it is important to note that many individuals with MVP are asymptomatic and may remain so throughout their lives. For those who do exhibit symptoms, the following are the key clinical features:Palpitations: This is a common symptom where individuals feel an irregular or rapid heartbeat. Palpitations in MVP are often due to arrhythmias such as premature ventricular contractions or supraventricular...
898