Metabolic Derangements in Lichen Planus - A Case Control Study.
Bikash Ranjan Kar1, Maitreyee Panda2, Nibedita Patro3
1Professor, Department of Skin and VD, IMS and SUM Hospital , Bhubaneswar, Odisha, India .
Journal of Clinical and Diagnostic Research : JCDR
|January 5, 2017
Summary
Patients with Lichen Planus (LP) show increased metabolic derangements, including abnormal lipid profiles and blood glucose levels. This study highlights a significant association between LP and metabolic issues.
Area of Science:
- Dermatology
- Internal Medicine
- Metabolic Disorders
Background:
- Psoriasis is linked to metabolic syndrome.
- Lichen Planus (LP) shares morphological similarities with psoriasis.
- Limited research exists on metabolic derangements in LP.
Purpose of the Study:
- To investigate the association between Lichen Planus and metabolic derangements.
- To assess metabolic parameters in LP patients compared to controls.
Main Methods:
- A prospective case-control study design.
- Inclusion of 40 LP patients (cases) and 40 controls with non-inflammatory diseases.
- Collection of data on height, weight, Body Mass Index (BMI), lipid profile, and fasting blood glucose.
Main Results:
- Higher mean values for lipid and glucose parameters observed in LP patients.
- Statistically significant differences (p-values) in metabolic parameters between cases and controls.
- Indication of prevalent metabolic derangements in the LP cohort.
Conclusions:
- Metabolic derangements are present in patients diagnosed with Lichen Planus.
- The findings suggest a potential link between LP and metabolic health.
- Further research is warranted to explore the underlying mechanisms and clinical implications.
