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Related Experiment Video

Updated: Mar 9, 2026

Sample Drift Correction Following 4D Confocal Time-lapse Imaging
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Drift Eliminating Designs for Non-Simultaneous Comparison Calibrations.

Ted Doiron1

  • 1National Institute of Standards and Technology, Gaithersburg, MD 20899-0001.

Journal of Research of the National Institute of Standards and Technology
|January 6, 2017
PubMed
Summary
This summary is machine-generated.

Drift effects in calibration are mitigated using comparison designs. These methods, initially for simultaneous mass comparisons, are adapted for non-simultaneous gage block calibrations, ensuring accurate measurements despite individual artifact testing.

Keywords:
calibration designcomparisondrift eliminatingleast squares analysismetrology

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Area of Science:

  • Metrology and Calibration Science
  • Measurement Assurance and Uncertainty

Background:

  • Instrumental drift significantly impacts calibration accuracy, particularly in comparative measurements.
  • The National Institute of Standards and Technology (NIST) has extensively researched drift compensation strategies.
  • Previous strategies focused on simultaneous comparison designs to inherently resist linear drift.

Purpose of the Study:

  • To extend drift-immune comparison designs to non-simultaneous measurement scenarios.
  • To address challenges in calibrating artifacts like gage blocks measured individually.
  • To develop mathematical methods for comparing non-simultaneously measured artifacts.

Main Methods:

  • Adaptation of linear drift-immune comparison designs.
  • Application to non-simultaneous measurement protocols.
  • Mathematical comparison of individually measured artifacts (e.g., gage blocks).

Main Results:

  • Demonstrated the efficacy of adapted comparison designs for non-simultaneous calibrations.
  • Provided a mathematical framework for comparing artifacts measured separately.
  • Successfully extended strategies immune to linear drift to new calibration contexts.

Conclusions:

  • The developed mathematical techniques effectively mitigate drift effects in non-simultaneous calibrations.
  • Comparison designs offer a robust strategy for accurate gage block calibration and similar measurements.
  • These methods enhance measurement assurance in metrology.