Concomitant CABG, Left Ventricular Restoration and Mitral Valve Repair for Ischemic Heart Disease
Yin Zhaohua1, Feng Wei1, Xu Fei1
1Department of Cardiac Surgery, Cardiovascular Institute and Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Insights
Combined coronary artery bypass grafting (CABG), surgical left ventricular restoration (LVR), and mitral valve repair (MVP) effectively treat ischemic heart disease with mitral regurgitation, showing good survival rates and improved heart function.
Area of Science:
- Cardiovascular Surgery
- Cardiac Surgery Outcomes
- Heart Valve Repair
Background:
- Ischemic heart disease often presents with left ventricular aneurysm and mitral regurgitation.
- Combined surgical interventions are explored for complex cardiac conditions.
Purpose of the Study:
- To assess the efficacy of combined CABG, LVR, and MVP for ischemic heart disease with mitral regurgitation.
- To compare different LVR and MVP strategies.
Main Methods:
- A cohort of 61 patients with left ventricular aneurysm and ischemic mitral regurgitation underwent combined CABG, LVR, and MVP from 2001-2015.
- Clinical and echocardiographic outcomes were evaluated over a mean follow-up of 5.8 years.
Main Results:
- Operative mortality was 4.9%; 1-, 5-, and 10-year survival rates were 95.1%, 86.9%, and 80.3%.
- Significant improvements in mitral regurgitation, left ventricular ejection fraction (LVEF), and left ventricular end diastolic diameter (LVEDD) were observed (P < .001).
- Clinical outcomes were not affected by specific LVR techniques or MVP approaches.
Conclusions:
- Combined CABG, LVR, and MVP is an effective treatment for ischemic left ventricular aneurysm with mitral regurgitation.
- The procedure offers acceptable operative risk and positive clinical outcomes.
Aim:
To evaluate the effects of combined coronary artery bypass grafting (CABG), surgical left ventricular restoration (LVR), and mitral valve repair (MVP) in treating ischemic heart disease combined with mitral regurgitation; and to evaluate the different strategies of LVR and MVP.
Methods:
From January 2001 to December 2015, 61 consecutive patients with left ventricular aneurysm and ischemic mitral regurgitation underwent concomitant CABG, LVR and MVP. We evaluated the clinical and echocardiographic outcomes of the patients. The mean follow-up was 5.8 ± 3.3 years.
Results:
The operative mortality was 4.9%. One-, five-, and ten-year survival rates were 95.1%, 86.9%, and 80.3%, respectively. Mitral regurgitation, left ventricular ejection fraction (LVEF), and left ventricular end diastolic diameter (LVEDD) improved significantly after surgery (P < .001). During follow-up, 3 patients (5.2%) had moderate mitral regurgitation and 1 patient (1.9%) had severe mitral regurgitation. The clinical outcomes were not influenced by the LVR technique and MVP approach.
Conclusion:
Combined CABG, LVR, and MVP was effective for ischemic left ventricular aneurysm with mitral regurgitation. The procedure was associated with acceptable operative risk and clinical outcomes.
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