Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Strain and Elastic Modulus

Strain and Elastic Modulus

The quantity that describes the deformation of a body under stress is known as strain. Strain is given as a fractional change in either length, volume, or geometry under tensile, volume (also known as bulk), or shear stress, respectively, and is a dimensionless quantity. The strain experienced by a body under tensile or compressive stress is called tensile or compressive strain, respectively. In contrast, the strain experienced under bulk stress and shear stress is known as volume and shear...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Advancing Spectroscopic Photoacoustic Imaging for Biomedical Applications: Opportunities, Challenges, and Pathways to Clinical Translation.

Applied spectroscopy·2026

Same author

Brain MR Elastography Metrics Associated with Alterations in Learning and Memory in People with HIV.

Research square·2026

Same author

Adjunctive Hybrid Telerehabilitation Is Associated With Comparable Clinical Outcomes to In-Person Physical Therapy After Shoulder Arthroplasty and Arthroscopic Rotator Cuff Repair: A Cohort Study.

Journal of shoulder and elbow surgery·2026

Same author

Monocyte Dll4 Contributes to Systemic Inflammation in People Living With HIV.

Circulation research·2026

Same author

Morphological feature remodeling of intracranial arteries in the context of inflammation and HIV-associated cognitive impairment.

medRxiv : the preprint server for health sciences·2026

Same author

HIV-Associated Microstructural Abnormalities in Default Mode, Executive Control, and Salience Networks: Insights from Tensor-Valued Diffusion Encoding.

Bioengineering (Basel, Switzerland)·2026

Search research articles

Related Experiment Video

Updated: Mar 9, 2026

Manufacturing Abdominal Aorta Hydrogel Tissue-Mimicking Phantoms for Ultrasound Elastography Validation

Manufacturing Abdominal Aorta Hydrogel Tissue-Mimicking Phantoms for Ultrasound Elastography Validation

Published on: September 19, 2018

Principal Strain Vascular Elastography: Simulation and Preliminary Clinical Evaluation.

Rohit Nayak¹, Steven Huntzicker¹, Jacques Ohayon²

¹Department of Electrical and Computer Engineering, University of Rochester, Rochester, New York, USA.

Ultrasound in Medicine & Biology

|January 7, 2017

Summary

Principal strain imaging with compounded plane wave imaging improves carotid artery mechanical property visualization. This method overcomes limitations of polar strain elastography, offering more reliable strain estimation for better diagnostic insights.

Keywords:

Anisotropy Atherosclerosis Plane wave imaging Principal strain Vascular elastography

More Related Videos

Monitoring the Wall Mechanics During Stent Deployment in a Vessel

Monitoring the Wall Mechanics During Stent Deployment in a Vessel

Published on: May 8, 2012

Using Digital Image Correlation to Characterize Local Strains on Vascular Tissue Specimens

Using Digital Image Correlation to Characterize Local Strains on Vascular Tissue Specimens

Published on: January 24, 2016

Related Experiment Videos

Last Updated: Mar 9, 2026

Manufacturing Abdominal Aorta Hydrogel Tissue-Mimicking Phantoms for Ultrasound Elastography Validation

Manufacturing Abdominal Aorta Hydrogel Tissue-Mimicking Phantoms for Ultrasound Elastography Validation

Published on: September 19, 2018

Monitoring the Wall Mechanics During Stent Deployment in a Vessel

Monitoring the Wall Mechanics During Stent Deployment in a Vessel

Published on: May 8, 2012

Using Digital Image Correlation to Characterize Local Strains on Vascular Tissue Specimens

Using Digital Image Correlation to Characterize Local Strains on Vascular Tissue Specimens

Published on: January 24, 2016

Area of Science:

Biomedical Ultrasound
Medical Imaging
Cardiovascular Mechanics

Background:

Accurate elastography of carotid arteries is crucial for assessing mechanical properties.
Traditional polar strain elastography faces challenges due to unknown vessel center.
Principal strain imaging offers an alternative but has limitations with displacement estimation.

Purpose of the Study:

To evaluate compounded plane wave imaging for principal strain elastography in carotid arteries.
To compare the accuracy and reliability of principal and polar strain elastograms.
To investigate the impact of fibrous cap thickness on strain distribution.

Main Methods:

Simulations of vessels with varying morphology and mechanical properties (isotropic, transversely isotropic).
Pilot study involving 10 healthy volunteers.
Compounded plane wave imaging for acquiring ultrasound data.
Calculation of principal and polar strain elastograms.

Main Results:

Principal strain elastograms demonstrated accuracy between 7% and 17%.
Strain concentration observed at the fibrous cap-vessel wall junction, decreasing with cap thickness.
Healthy volunteer elastograms showed spatial asymmetry, consistent with transversely isotropic models.
No significant difference in mean strain between principal and polar methods (p > 0.05).

Conclusions:

Compounded plane wave imaging enhances the reliability of principal strain elastography for carotid arteries.
This approach mitigates issues associated with imprecise vessel center estimation in polar strain elastography.
Principal strain elastography provides valuable insights into carotid artery biomechanics and plaque characterization.