[An in vivo study of inorganic bone particle-impregnated bone cement]

According to definite proportion by weight, inorganic bone particles were impregnated into bone cement and then used for the fixation of implanted artificial femoral head in a series of canines. Upon successive observations, new bone was seen to have already been growing into the bone cement one month post operatively, and active growth going on with bone tissue passing through the whole layer of cement three months after operation. In the fifth month's specimens, most of the inorganic bone particles were replaced by new bone tissue while slices of one year post operation showed that the bone tissue was mature and the activity of bone formation ceased. The biological fixation effect produced by bone ingrowth was found to have increased the shearing strength of cement-bone interface to 1.4-3.6 times of the control side and the stability of prosthesis was improved obviously. The bone-particle-impregnated bone cement has already been using in our clinical practice since 1987.