Related Experiment Video
Updated: Mar 9, 2026
09:22
Method of Direct Segmental Intra-hepatic Delivery Using a Rat Liver Hilar Clamp Model
Published on: April 2, 2017
14.8K
Laboratory Evaluation of the Liver.
Yuri A Lawrence1, Jörg M Steiner1
1Gastrointestinal Laboratory, Department of Veterinary Small Animal Clinical Sciences, College of Veterinary Medicine & Biomedical Sciences, Texas A&M University, 4474 TAMU, College Station, TX 77843-4474, USA.
The Veterinary Clinics of North America. Small Animal Practice
|January 9, 2017
Summary
This review covers key laboratory tests for diagnosing and monitoring liver diseases in pets. Understanding liver enzyme activities and function tests is crucial for accurate veterinary assessment.
Area of Science:
- Veterinary Medicine
- Clinical Pathology
Background:
- Laboratory evaluation is vital for diagnosing and monitoring hepatobiliary diseases in animals.
- Serum liver enzymes indicate hepatocellular injury or cholestasis.
- Liver function tests assess synthetic capacity, ammonia levels, and bile acids.
Purpose of the Study:
- To review common laboratory parameters for diagnosing hepatobiliary disorders in dogs and cats.
- To emphasize the importance of understanding test performance and limitations.
Main Methods:
- Review of existing literature on laboratory diagnostics for hepatobiliary diseases.
- Categorization of liver enzyme activities and function tests.
Main Results:
- Laboratory tests provide essential data for diagnosing and monitoring liver conditions.
- Different tests reflect specific aspects of liver health, such as injury, cholestasis, or function.
Conclusions:
- Appropriate use of laboratory tests requires understanding their characteristics and limitations.
- This review aids veterinarians in selecting and interpreting tests for canine and feline hepatobiliary disorders.
Related Concept Videos
01:22Effect of Hepatic Disease on Pharmacokinetics: Pathophysiologic Assessment and Liver Function Test
245
In clinical practice, the direct measurement of hepatic blood flow to evaluate liver function presents significant challenges due to the intricate and specialized nature of the necessary techniques. Consequently, healthcare professionals often rely on empirical estimates derived from thorough patient examinations and liver function tests to gauge liver health. Among the tools at their disposal, the Child–Pugh and MELD scoring systems stand out for their ability to categorize and assess...
245
01:27Liver Histology
5.2K
The microscopic anatomy of the liver is a complex and intricate system that comprises numerous structural units known as liver lobules, each of which is comparable in size to a sesame seed. These hexagonal structures consist of plates of liver cells or hepatocytes, which are characterized by their versatility and abundance of cellular apparatus like rough and smooth ER, Golgi apparatus, peroxisomes, and mitochondria.
Hepatocytes perform a variety of essential functions. They secrete...
Hepatocytes perform a variety of essential functions. They secrete...
5.2K
01:30Liver Physiology
4.1K
The liver, an essential organ in the human body, performs over 200 vital functions that can be broadly categorized into metabolic, hematological, endocrine regulation, and bile production.
Metabolic Regulation:
The liver is the central organ involved in regulating blood composition. It stabilizes blood glucose levels, maintaining them within the range of 70–110 mg/dL. When these levels drop, the liver breaks down glycogen reserves and releases glucose into the bloodstream. It can...
Metabolic Regulation:
The liver is the central organ involved in regulating blood composition. It stabilizes blood glucose levels, maintaining them within the range of 70–110 mg/dL. When these levels drop, the liver breaks down glycogen reserves and releases glucose into the bloodstream. It can...
4.1K
01:17Gross Anatomy of the Liver
2.4K
The liver, the largest gland within the human body, is a firm and reddish-brown organ. This wedge-shaped structure weighs approximately 1.5 kg and occupies a significant portion of the right hypochondriac and epigastric regions. It extends more to the right of the body's midline than to the left.
Located under the diaphragm, the liver is almost entirely ensconced within the rib cage, providing it with substantial protection. Except for the superior most bare area, the liver's surface is...
Located under the diaphragm, the liver is almost entirely ensconced within the rib cage, providing it with substantial protection. Except for the superior most bare area, the liver's surface is...
2.4K
01:26Effect of Hepatic Disease on Pharmacokinetics: Drug Dosing and Hepatic Blood Flow
305
Chronic liver disease significantly impacts drug metabolism due to alterations in hepatic blood flow and enzyme accessibility. This disruption affects the body's pharmacokinetics—the movement and processing of drugs within the system. Key enzymes crucial for metabolizing medications become less accessible, changing how drugs are processed and utilized. Furthermore, liver disease influences the synthesis of plasma proteins, such as albumin and globulins, which play critical roles in drug...
305
01:30Serum Laboratory Studies, Stool Test, Breath Test
1.0K
Gastrointestinal (GI) diagnostic studies are pivotal in confirming, ruling out, diagnosing, or staging various diseases, including cancers. Following diagnosis, allocating time for discussions with the patient and providing informational resources is crucial. Diagnostic assessments of the GI tract often occur in outpatient settings like endoscopy suites or GI labs. Preparation for these tests may include dietary restrictions, fasting, liquid bowel preparations, laxatives, enemas, and the...
1.0K