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Updated: Mar 9, 2026

A Fluorescence-based Method to Study Bacterial Gene Regulation in Infected Tissues
Published on: February 19, 2019
Enzyme-responsive reporter molecules for selective localization and fluorescence imaging of pathogenic biofilms
Junxin Aw1, Frances Widjaja1, Yichen Ding2
1Division of Chemistry and Biological Chemistry, School of Physical & Mathematical Sciences, Nanyang Technological University, Singapore, 637371, Singapore. bengang@ntu.edu.sg.
Abstract:
Pathogenic bacteria and their biofilm formation are responsible for a broad spectrum of microbial infections. A novel enzyme-responsive reporter molecule (ERM-1), which can specifically recognize AmpC β-lactamase (Bla) in drug resistant bacteria, has been developed to enable the selective localization of biofilms.
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