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Contact-dependent Signaling

Contact-dependent Signaling

Contact-dependent signaling, as the name suggests, requires that communicating cells be in direct contact with each other. This is achieved either through receptor-ligand interactions or by specialized cytoplasmic channels that allow the flow of small molecules between cells. In animal cells, channels called gap junctions facilitate contact-dependent signaling in certain tissues, whereas, plasmodesmata perform a similar function in plants.
Gap Junctions
In animal cells, gap junctions are formed...

Lenz's Law

Lenz's Law

The direction in which the induced emf drives the current around a wire loop can be found through the negative sign. However, it is usually easier to determine this direction with Lenz's law, named in honor of its discoverer, Heinrich Lenz (1804–1865). Lenz's law states that the direction of the induced emf drives the current around a wire loop always to oppose the change in magnetic flux that causes the emf.
If a bar magnet is moved toward a coil such that the magnetic flux...

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Spatial Quantification of Drugs in Pulmonary Tuberculosis Lesions by Laser Capture Microdissection Liquid Chromatography Mass Spectrometry LCM-LC/MS

Spatial Quantification of Drugs in Pulmonary Tuberculosis Lesions by Laser Capture Microdissection Liquid Chromatography Mass Spectrometry LCM-LC/MS

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Reply to L.B. Marks et al

Abram Recht¹, Elizabeth A Comen¹, Richard E Fine¹

¹Abram Recht, Beth Israel Deaconess Medical Center, Boston, MA; Elizabeth A. Comen, Memorial Sloan Kettering Cancer Center, New York, NY; Richard E. Fine, The West Clinic Comprehensive Breast Center, Germantown, TN; Gini F. Fleming, University of Chicago Medical Center, Chicago, IL; Patricia H. Hardenbergh, Shaw Regional Cancer Center, Edwards, CO; Alice Y. Ho, Memorial Sloan Kettering Cancer Center, New York, NY; Clifford A. Hudis, American Society of Clinical Oncology, Alexandria, VA; E. Shelley Hwang, Duke University Medical Center, Durham, NC; Jeffrey J. Kirshner, Hematology-Oncology Associates of Central New York, East Syracuse, NY; Monica Morrow, Memorial Sloan Kettering Cancer Center, New York, NY; Kilian E. Salerno, Roswell Park Cancer Institute, Buffalo, NY; George W. Sledge Jr, Stanford University Medical Center, Palo Alto, CA; Lawrence J. Solin, Albert Einstein Healthcare Network, Philadelphia, PA; Patricia A. Spears, North Carolina State University, Raleigh, NC; Timothy J. Whelan, McMaster University, Hamilton, Ontario, Canada; Mark R. Somerfield, American Society of Clinical Oncology, Alexandria, VA; and Stephen B. Edge, Roswell Park Cancer Institute, Buffalo, NY.

Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology

|January 10, 2017

Summary

No abstract available in PubMed .

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