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Endotoxin-induced ascites formation in the rat: partial mediation by platelet-activating factor

F Guarner1, J L Wallace, W K MacNaughton

  • 1Liver Unit, Hospital Clínic i Provincial, Barcelona, Spain.

Summary

Bacterial endotoxin causes liver injury, ascites, and gastrointestinal issues. Platelet-activating factor (PAF) mediates these effects, as blocking PAF reduces endotoxin-induced damage in rats.

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