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Fulminant diptheretic myocarditis.

P V Havaldar, V D Patil, B M Siddibhavi

    Indian Heart Journal
    |July 1, 1989
    PubMed
    Summary
    This summary is machine-generated.

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    Fulminant diphtheritic myocarditis can cause severe heart complications, including heart block and ventricular tachycardia. Early electrocardiogram (ECG) abnormalities and elevated SGOT levels indicate a poorer prognosis in affected children.

    Area of Science:

    • Cardiology
    • Infectious Diseases
    • Pediatrics

    Background:

    • Diphtheria, a bacterial infection, can lead to severe complications beyond the respiratory tract.
    • Myocarditis, inflammation of the heart muscle, is a serious but less common manifestation of diphtheria.

    Observation:

    • This study describes five pediatric cases of fulminant diphtheritic myocarditis.
    • Three cases presented with extensive faucial diphtheria, while two had minor electrocardiogram (ECG) abnormalities.
    • Severe diphtheria cases exhibited significant cardiac arrhythmias, including atrioventricular dissociation, left bundle branch block (LBBB) with complete heart block, and ventricular tachycardia.

    Findings:

    • Three out of five children with fulminant diphtheritic myocarditis died.
    • All fatal cases exhibited major ECG abnormalities, suggesting their prognostic significance.

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  • Serum Glutamic Oxaloacetic Transaminase (SGOT) levels were also correlated with patient outcomes.

    • Implications:

    • Fulminant diphtheritic myocarditis carries a high mortality rate, especially in children with significant ECG changes.
    • ECG monitoring and SGOT levels are crucial for assessing prognosis in pediatric diphtheria patients.
    • Prompt recognition and management of diphtheritic myocarditis are essential for improving survival rates.