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Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases
Published on: July 28, 2013
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Identification of early neurodegenerative change in presymptomatic spinocerebellar ataxia type 1: A diffusion tensor
1Department of Rehabilitation Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Seocho-Gu, Seoul, 06591, Republic of Korea.
Parkinsonism & Related Disorders
|January 12, 2017
Abstract:
We report a 41-year-old man of presymptomatic spinocerebellar ataxia type 1. Diffusion tensor imaging (DTI) verified decreased fractional anisotropy of cerebellar afferent and efferent pathways compared to 5 age-matched healthy controls while conventional MRI revealed normal brain. DTI was valuable in detection of early microstructural damage of cerebellar pathways.
