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Updated: Mar 9, 2026
06:01
A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
Published on: August 18, 2015
15.6K
[Thrombolysis in stroke mimics: Experience in 10 cases]
Alejandro M Brunser1, Arnold Hoppe1, Paula Muñoz1
1Unidad de Tratamiento del Ataque Cerebrovascular, Servicio de Neurología, Departamento de Medicina, Clínica Alemana de Santiago, Santiago, Chile.
Revista Medica De Chile
|January 12, 2017
Summary
Intravenous thrombolysis (IVT) for stroke mimics (SM) is uncommon but safe. These patients showed no bleeding complications and had favorable outcomes at three months.
Area of Science:
- Neurology
- Emergency Medicine
- Pharmacology
Background:
- Intravenous thrombolysis (IVT) effectiveness in cerebral ischemia is time-sensitive.
- Stroke mimics (SM) are frequently encountered in emergency departments.
- Rapid treatment protocols may lead to IVT administration in SM.
Purpose of the Study:
- To determine the frequency of stroke mimics receiving IVT.
- To evaluate the prognosis of stroke mimics treated with IVT.
Main Methods:
- Prospective analysis of patients with suspected acute ischemic stroke (AIS) in a Chilean clinic (2004-2015).
- Identified SM treated with IVT.
- Assessed symptomatic cerebral hemorrhage, extracranial bleeding, and functional status at 3 months (modified Rankin Scale).
Main Results:
- Out of 1,417 suspected AIS patients, 240 (16.9%) were SM.
- 10 out of 197 (5%) patients treated with IVT were SM.
- All SM patients receiving IVT were functionally independent at 3 months with no bleeding complications.
Conclusions:
- Stroke mimics are occasionally treated with IVT.
- IVT in SM was not associated with bleeding complications.
- Prognosis for SM treated with IVT is favorable at three months.
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