Related Experiment Video
Updated: Mar 9, 2026

07:34
A Cost-effective and Reliable Method to Predict Mechanical Stress in Single-use and Standard Pumps
Published on: August 5, 2015
9.9K
Baxter elastomeric pumps: Weighing as an alternative to visual inspection.
Ellen L Cusano1, Raafi Ali2, Michael B Sawyer2
11 Faculty of Medicine, University of Ottawa, ON, Canada.
Summary
Weighing Baxter Infusor pumps offers a more accurate method for monitoring 5-fluorouracil (5FU) infusions compared to visual inspection. This validated technique empowers patients and healthcare professionals with objective data, reducing concerns about dosing accuracy.
Area of Science:
- Oncology
- Pharmacology
- Medical Devices
Background:
- Elastomeric pumps are commonly used for 46-hour infusions of 5-fluorouracil (5FU).
- Current Baxter recommendations advise patients to visually monitor infusion pumps, which can lead to confusion and anxiety regarding accurate dosing.
- Weighing elastomeric pumps has not been previously validated as a monitoring method by Baxter.
Purpose of the Study:
- To validate the accuracy of weighing Baxter Infusor pumps as a method for monitoring 5-fluorouracil (5FU) infusions.
- To assess real-world variability in Baxter Infusor pump performance.
- To compare patient preference between weighing and visual inspection of infusion pumps.
Main Methods:
- Patients receiving 46-hour 5FU infusions returned to the clinic around 24 hours post-initiation.
- Infusion pumps were weighed using a standard kitchen scale, with date, time, and weight recorded.
- Patients were surveyed regarding their preference for pump monitoring methods (weighing vs. visual inspection).
Main Results:
- 103 Baxter Infusor pumps were weighed between 17.25 and 27.5 hours of infusion.
- The majority of pumps (99/103) weighed less than expected, indicating average flow rates within the acceptable 10% variability.
- Among patients with a preference, over twice as many favored pump weighing over visual inspection.
Conclusions:
- Weighing Baxter Infusor pumps using common kitchen scales is a viable and objective alternative to visual inspection.
- Patient education is key to the successful adoption of pump weighing for monitoring 5FU infusions.
- This method can enhance patient confidence and reduce concerns about under- or over-dosing during chemotherapy administration.
More Related Videos
Related Concept Videos
Pumped Concrete
443
Concrete in large quantities can be pumped across long distances for placing in inaccessible sites. This system comprises a hopper that receives concrete from a mixer, a pump to propel the concrete, and pipelines that facilitate its delivery.
For direct-acting pumps, the concrete enters the pump via the inlet valve under the action of gravity and suction created by the movement of the piston. This concrete is then forced into the pipeline and out through the outlet valve by the forward movement...
For direct-acting pumps, the concrete enters the pump via the inlet valve under the action of gravity and suction created by the movement of the piston. This concrete is then forced into the pipeline and out through the outlet valve by the forward movement...
443
ATP Driven Pumps III: V-type Pumps
5.0K
V-type pumps are ATP-driven pumps found in the vacuolar membranes of plants, yeast, endosomal and lysosomal membranes of animal cells, plasma membranes of a few specialized eukaryotic cells, and some prokaryotes. They are also known as the V1Vo-ATPase, that couple ATP hydrolysis to transport protons against a concentration gradient.
The peripheral or cytosolic V1 domain with eight subunits is involved in ATP hydrolysis. The integral or transmembrane V0 domain containing at least five subunits...
The peripheral or cytosolic V1 domain with eight subunits is involved in ATP hydrolysis. The integral or transmembrane V0 domain containing at least five subunits...
5.0K

