Related Experiment Video
Updated: Mar 9, 2026

Determining Immune System Suppression versus CNS Protection for Pharmacological Interventions in Autoimmune Demyelination
Published on: September 12, 2016
Etanercept in the treatment of refractory SAPHO syndrome
1Department of Rheumatology & Immunology, Shengli Oilfield Central Hospital Dongying, China.
Objective:
To explore the application and efficacy of TNF-α inhibitors in the treatment of SAPHO syndrome.
Methods:
Two cases of refractory SAPHO syndrome were successfully treated with etanercept. And pain scores, laboratory parameters and functional index were used to judge the efficacies. Literature was also systemically reviewed.
Results:
Both patients achieved marked clinical remission. There was no obvious toxic or adverse response.
Conclusion:
Etanercept has rapid and definite efficacies in the treatment of patients with refractory SAPHO syndrome.
More Related Videos
Related Concept Videos
Drugs for Treatment of Crohn's Disease in IBD Using Biologic Agents: Anti-TNF
Drugs for Treatment of Crohn's Disease in IBD Using Immunomodulatory Agents
Treatment for Pulmonary Arterial Hypertension: Endothelin Receptor Antagonists
ETs are synthesized through a complex sequence of enzymatic steps, primarily involving an enzyme referred to as endothelin-converting enzyme...
Autoimmune Disorders
Concept and Mechanism of Autoimmune Diseases
The immune...
Nephrotic Syndrome II : Assessment and Medical Management
Nephrotic Syndrome I : Introduction

