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Apocynin derivatives from Iris tectorum.

Chun-Lei Zhang1,2, Guo-Ru Shi1, Yan-Fei Liu1

  • 1a State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica , Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing 100050 , China.

Journal of Asian Natural Products Research
|January 14, 2017
PubMed
Summary
This summary is machine-generated.

Researchers identified new apocynin derivatives from Iris tectorum rhizomes. This study details the chemical structures of these novel compounds and known related substances.

Keywords:
Iris tectorumPhytochemical investigationapocynin derivativesisolation and characterization

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Area of Science:

  • Natural Product Chemistry
  • Phytochemistry
  • Organic Chemistry

Background:

  • Iris tectorum (Thunb.) Maxim. is a plant species known for its medicinal properties.
  • Apocynin derivatives are a class of compounds with potential biological activities.
  • Rhizomes are underground plant stems that can be rich sources of bioactive metabolites.

Purpose of the Study:

  • To isolate and characterize new and known compounds from the rhizomes of Iris tectorum.
  • To elucidate the structures of these isolated phytochemicals using spectroscopic methods.
  • To contribute to the understanding of the chemical constituents of Iris tectorum.

Main Methods:

  • Phytochemical investigation of Iris tectorum rhizomes.
  • Isolation of compounds using chromatographic techniques.
  • Structure elucidation via comprehensive spectroscopic data analysis (e.g., NMR, MS).

Main Results:

  • Isolation and characterization of three new apocynin derivatives: apocynin-4-O-β-D-(6'-O-syringyl)glucopyranoside (1), scrophenoside C-7-ethyl ether (2, 3).
  • Identification of a new, synthetically known compound, apocynin-4-O-β-D-xylopyranoside (4).
  • Characterization of five additional known compounds (5-9) from the plant extract.

Conclusions:

  • The study successfully identified novel apocynin derivatives from Iris tectorum rhizomes.
  • The structural elucidation provides valuable data on the phytochemical profile of this plant species.
  • These findings expand the knowledge of natural products and their chemical diversity.