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Does coffee consumption alter plasma lipoprotein(a) concentrations? A systematic review
Peter Penson1, Maria-Corina Serban2, Sorin Ursoniu3
1a School of Pharmacy and Biomolecular Sciences , Liverpool John Moores University , Liverpool , UK.
Critical Reviews in Food Science and Nutrition
|January 14, 2017
Summary
Coffee
Area of Science:
- Cardiovascular Health
- Nutritional Science
- Lipid Metabolism
Background:
- Coffee consumption impacts plasma lipids and cholesterol.
- Limited research exists on coffee's effect on lipoprotein(a) (Lp(a)).
Purpose of the Study:
- To systematically review the role of coffee consumption on serum Lp(a) concentrations.
- To synthesize findings from trials and epidemiological studies on coffee and Lp(a).
Main Methods:
- PRISMA-compliant systematic review.
- Searched PubMed, Scopus, Web of Science, and Cochrane Central databases.
- Included six publications with nine experimental trials and 640 participants.
Main Results:
- Short-term coffee consumption showed a reduction in serum Lp(a) (≤11 mg/dL) in 6 trials or no effect in 2 trials.
- One cross-sectional study indicated elevated Lp(a) in chronic boiled coffee consumers compared to filtered coffee consumers.
- Coffee's effect on Lp(a) appears complex, potentially biphasic, and influenced by preparation method.
Conclusions:
- The impact of coffee on serum Lp(a) is intricate and preparation-dependent.
- Further research is needed to elucidate the biphasic time-course and preparation-specific effects.
- Understanding these effects is crucial for cardiovascular health recommendations.
