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Simultaneous determination of benzene and toluene in the blood using head-space gas chromatography
K Pekari1, M L Riekkola, A Aitio
1Institute of Occupational Health, Laboratory of Biochemistry, Helsinki, Finland.
Journal of Chromatography
|July 21, 1989
Abstract:
A head-space method for the simultaneous determination of benzene and toluene in blood using a gas chromatograph equipped with a photoionization detector was developed. Internal standards for benzene and toluene were fluorobenzene and o-xylene, respectively, and the detection limit was 5 nmol/l for both solvents. This method is sensitive enough for needs of biological monitoring of benzene and toluene in exposed workers. With automation it offers a possibility for routine measurements. An application of the method in monitoring exposed workers in the industry is presented.