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Bladder dysfunction in multiple sclerosis: a 6-year follow-up study.

Darija Kisic Tepavcevic1, Tatjana Pekmezovic1, Irena Dujmovic Basuroski2

  • 1Institute of Epidemiology, Faculty of Medicine, University of Belgrade, Visegradska 26, Belgrade, 11000, Serbia.

Acta Neurologica Belgica
|January 17, 2017
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Summary
This summary is machine-generated.

Bladder dysfunction (BD) significantly increases over time in multiple sclerosis (MS) patients, impacting quality of life. Urgency of urination is the most common symptom, correlating with disability and sexual dysfunction.

Keywords:
Bladder dysfunctionMultiple sclerosisQuality of life

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Area of Science:

  • Neurology
  • Urology
  • Autonomic Neuroscience

Background:

  • Bladder dysfunction (BD) is a prevalent yet often overlooked autonomic disturbance in multiple sclerosis (MS).
  • Understanding the progression of BD symptoms and their impact is crucial for patient management.

Purpose of the Study:

  • To longitudinally track changes in BD symptom frequency in an MS cohort over 6 years.
  • To examine correlations between BD symptoms, clinical MS characteristics, and health-related quality of life (HRQoL).

Main Methods:

  • A longitudinal study of 93 MS patients (McDonald's criteria, 2001).
  • Assessment of BD symptoms, Expanded Disability Status Scale, depression, fatigue, sexual function, and HRQoL at baseline, 3, and 6 years.
  • Statistical analysis to identify correlations and changes over time.

Main Results:

  • The proportion of patients with BD symptoms significantly increased from baseline (48.1% males, 45.5% females) to 6-year follow-up (71.4% males, 66.7% females).
  • Urgency of urination was the most frequent BD symptom.
  • BD presence correlated significantly with increased physical disability, sexual dysfunction, and reduced HRQoL at all follow-up points.

Conclusions:

  • Bladder dysfunction is highly frequent in MS patients and tends to worsen over time.
  • BD significantly impacts physical disability, sexual function, and HRQoL in MS patients.
  • Early recognition and management of BD are essential in multiple sclerosis care.